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Assay Detail

CHEMBL843985

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity was determined
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Structural correlations of choline acetyltransferase inhibitors: trans-N-(carboxymethyl)-4-(beta-1-naphthylvinyl)pyridinium bromide and cis-N-(2-aminoethyl)-4-(beta-1-naphthylvinyl)-3-methylpyridinium bromide hydrobromide.
Chweh AY, DeBernardis JF, Siuda JF, Rondan NG, Abola JE, Abraham DJ.
J Med Chem (1984) 27 : 825 -830
PubMed 6737426 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.73 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL353384 2 5.30
CHEMBL19418 1 4.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL353384 IC50 = 5000.0 nM 5.30
CHEMBL19418 IC50 = 25000.0 nM 4.60
CHEMBL353384 IC50 = 50000.0 nM 4.30