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Assay Detail

CHEMBL844000

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for hydroxyl radical (OH) scavenging activity
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Antioxidant properties of nitrocaffeic acids
Grenier J, Cotelle N, Cotelle P, Catteau J
Bioorg Med Chem Lett (1996) 6 : 431 -434
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 9 6.12 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL280998 CATECHOL 1 8.00
CHEMBL145 CAFFEIC ACID 3.0 1 6.30
CHEMBL136998 1 4.07
CHEMBL137554 1 -
CHEMBL288446 1 -
CHEMBL137295 1 -
CHEMBL42423 4-Nitrocatechol 1 -
CHEMBL137555 1 -
CHEMBL137762 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL280998 CATECHOL IC50 = 10.0 nM 8.00
CHEMBL145 CAFFEIC ACID IC50 = 500.0 nM 6.30
CHEMBL136998 IC50 = 85000.0 nM 4.07
CHEMBL137554 IC50 = 300000.0 nM -
CHEMBL288446 IC50 = 180000.0 nM -
CHEMBL137295 IC50 = 250000.0 nM -
CHEMBL42423 4-Nitrocatechol IC50 = 130000.0 nM -
CHEMBL137555 IC50 = 400000.0 nM -
CHEMBL137762 IC50 = 425000.0 nM -