Assay Detail
Functional
CHEMBL844146
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Activity in histone hyperacetylation assay in cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design, synthesis, and activity of HDAC inhibitors with a N-formyl hydroxylamine head group.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.48 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 6.16 |
| CHEMBL140525 | — | — | 1 | 5.29 |
| CHEMBL336935 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | EC50 | = | 700.0 | nM | 6.16 |
| CHEMBL140525 | — | EC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL336935 | — | EC50 | = | 10000.0 | nM | 5.00 |