Assay Detail
Functional
CHEMBL844726
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Effect on the transcription and release of thymidine kinase in a reporter-gene assay (RGA)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
7-Oxa[2.2.1]bicycloheptane-2,3-dicarboxylic acid derivatives as phosphatase inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.13 | 4.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL314035 | — | — | 1 | 4.38 |
| CHEMBL315040 | — | — | 1 | 4.00 |
| CHEMBL8327 | DEMETHYL-CANTHARIDIN | — | 1 | 4.00 |
| CHEMBL160 | CYCLOSPORINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL314035 | — | IC50 | = | 42000.0 | nM | 4.38 |
| CHEMBL315040 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL8327 | DEMETHYL-CANTHARIDIN | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL160 | CYCLOSPORINE | IC50 | > | 1000.0 | nM | - |