Assay Detail
Functional
CHEMBL844736
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In vitro inhibitory concentration expressed as thrombin time of the compound
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Biaryl substituted alkylboronate esters as thrombin inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.79 | 7.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL290376 | — | — | 1 | 7.26 |
| CHEMBL418071 | — | — | 1 | 6.96 |
| CHEMBL40854 | — | — | 1 | 6.85 |
| CHEMBL287964 | — | — | 1 | 6.65 |
| CHEMBL289318 | — | — | 1 | 6.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL290376 | — | IC50 | = | 55.0 | nM | 7.26 |
| CHEMBL418071 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL40854 | — | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL287964 | — | IC50 | = | 225.0 | nM | 6.65 |
| CHEMBL289318 | — | IC50 | = | 600.0 | nM | 6.22 |