Assay Detail

CHEMBL845005

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antagonist activity was determined

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Synthesis and in vitro LTD4 antagonist activity of bicyclic and monocyclic cyclopentylurethane and cyclopentylacetamide N-arylsulfonyl amides.

Matassa VG, Brown FJ, Bernstein PR, Shapiro HS, Maduskuie TP, Cronk LA, Vacek EP, Yee YK, Snyder DW, Krell RD.
J Med Chem (1990) 33 : 2621 -2629
PubMed 2167983 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Kd	1	10.10	10.10

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL22033	ICI-198615	—	1	10.10

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL22033	ICI-198615	Kd	=	0.07943	nM	10.10