Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL846058

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Concentration required for inhibitory activity against human sorbitol dehydrogenase (SDH)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Sorbitol dehydrogenase (CHEMBL2275)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Modelling studies of the active site of human sorbitol dehydrogenase: an approach to structure-based inhibitor design of the enzyme.
Darmanin C, El-Kabbani O.
Bioorg Med Chem Lett (2001) 11 : 3133 -3136
PubMed 11720859 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL90488 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL90488 IC50 = 1000.0 nM 6.00