Assay Detail
Binding
CHEMBL846100
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Tested for [3H]DTG binding to sigma-2 receptor in NG108-15 membrane
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Expert |
Publication
Evaluation of the effects of the enantiomers of reduced haloperidol, azaperol, and related 4-amino-1-arylbutanols on dopamine and sigma receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.73 | 8.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL129237 | — | — | 1 | 8.09 |
| CHEMBL54 | HALOPERIDOL | 4.0 | 1 | 7.58 |
| CHEMBL129159 | — | — | 1 | 7.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL129237 | — | Ki | = | 8.2 | nM | 8.09 |
| CHEMBL54 | HALOPERIDOL | Ki | = | 26.0 | nM | 7.58 |
| CHEMBL129159 | — | Ki | = | 31.0 | nM | 7.51 |