Assay Detail
Binding
CHEMBL846956
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Compound was tested for percentage inhibition of phosphomannose isomerase enzyme of Candida albicans (CaPMI).
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Candida albicans |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Exploring structure-activity relationships around the phosphomannose isomerase inhibitor AF14049 via combinatorial synthesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.81 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL419459 | — | — | 1 | 5.22 |
| CHEMBL76175 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL419459 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL76175 | — | IC50 | = | 40000.0 | nM | 4.40 |