Assay Detail
Binding
CHEMBL847115
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Inhibitory concentration against plasmin.
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
RATIONAL DESIGN, SYNTHESIS, AND SERINE PROTEASE INHIBITORY ACTIVITY OF NOVEL P1-ARGININOYL HETEROCYCLES
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.87 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL28968 | — | — | 1 | 7.85 |
| CHEMBL436851 | — | — | 1 | 5.88 |
| CHEMBL538226 | — | — | 1 | - |
| CHEMBL27008 | — | — | 1 | - |
| CHEMBL544222 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL28968 | — | IC50 | = | 14.2 | nM | 7.85 |
| CHEMBL436851 | — | IC50 | = | 1320.0 | nM | 5.88 |
| CHEMBL538226 | — | IC50 | > | 2500.0 | nM | - |
| CHEMBL27008 | — | IC50 | > | 2500.0 | nM | - |
| CHEMBL544222 | — | IC50 | < | 25.0 | nM | - |