Assay Detail
Binding
CHEMBL847684
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Compound was tested for inhibition against tissue factor.
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Pyrazoles, 1,2,4-triazoles, and tetrazoles as surrogates for cis-amide bonds in boronate ester thrombin inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 5.57 | 5.83 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2373440 | — | — | 1 | 5.83 |
| CHEMBL2373559 | — | — | 1 | 5.57 |
| CHEMBL2373397 | — | — | 1 | 5.57 |
| CHEMBL2373475 | — | — | 1 | 5.44 |
| CHEMBL2373302 | — | — | 1 | 5.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2373440 | — | Ki | = | 1490.0 | nM | 5.83 |
| CHEMBL2373559 | — | Ki | = | 2700.0 | nM | 5.57 |
| CHEMBL2373397 | — | Ki | = | 2700.0 | nM | 5.57 |
| CHEMBL2373475 | — | Ki | = | 3600.0 | nM | 5.44 |
| CHEMBL2373302 | — | Ki | = | 3700.0 | nM | 5.43 |