Assay Detail
Binding
CHEMBL849995
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Enzyme kinetic inhibition constant against tripeptide, Hip-His-Leu as substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of a ketomethylene analogue of a tripeptide inhibitor of angiotensin converting enzyme.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.06 | 7.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1560 | CAPTOPRIL | 4.0 | 1 | 7.15 |
| CHEMBL435360 | — | — | 1 | 6.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1560 | CAPTOPRIL | Ki | = | 71.5 | nM | 7.15 |
| CHEMBL435360 | — | Ki | = | 106.0 | nM | 6.97 |