Assay Detail
Functional
CHEMBL853226
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Inhibition of superoxide radical scavenging activity
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Intermediate |
Publication
Biological evaluation, chelation, and molecular modeling studies of novel metal-chelating inhibitors of NF-kappaB-DNA binding: structure activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.18 | 4.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL210287 | BROMOPYROGALLOL RED | — | 1 | 4.29 |
| CHEMBL210208 | PYROGALLOL RED | — | 1 | 4.06 |
| CHEMBL413576 | ERIOCHROME CYANINE R | — | 1 | - |
| CHEMBL377545 | CHROME AZUROL S | — | 1 | - |
| CHEMBL210574 | PYROCATECHOL VIOLET | — | 1 | - |
| CHEMBL1057 | FLUORESCEIN | 4.0 | 1 | - |
| CHEMBL210868 | AURIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL210287 | BROMOPYROGALLOL RED | IC50 | = | 51500.0 | nM | 4.29 |
| CHEMBL210208 | PYROGALLOL RED | IC50 | = | 88000.0 | nM | 4.06 |
| CHEMBL413576 | ERIOCHROME CYANINE R | IC50 | > | 250000.0 | nM | - |
| CHEMBL377545 | CHROME AZUROL S | IC50 | > | 250000.0 | nM | - |
| CHEMBL210574 | PYROCATECHOL VIOLET | IC50 | = | 120000.0 | nM | - |
| CHEMBL1057 | FLUORESCEIN | IC50 | - | — | - | |
| CHEMBL210868 | AURIN | IC50 | - | — | - |