Assay Detail
Functional
CHEMBL853483
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Antiviral activity against Human CMV T2211 in HFF cells by SEAP assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human betaherpesvirus 5 |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Multidrug resistance conferred by novel DNA polymerase mutations in human cytomegalovirus isolates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.66 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5314375 | CIDOFOVIR | 4.0 | 1 | 6.70 |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | 5.89 |
| CHEMBL666 | FOSCARNET | 4.0 | 1 | 4.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5314375 | CIDOFOVIR | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL182 | GANCICLOVIR | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL666 | FOSCARNET | IC50 | = | 41000.0 | nM | 4.39 |