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Assay Detail

CHEMBL853835

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of MCMV replication in MEF cells by plaque reduction assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Murid betaherpesvirus 1
Cell Type MEF
Confidence 1 — Organism
Curated By Expert

Target

Murid betaherpesvirus 1 (CHEMBL613495)
Type ORGANISM
Organism Murid betaherpesvirus 1

Publication

9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1.
Zhou S, Kern ER, Gullen E, Cheng YC, Drach JC, Tamiya S, Mitsuya H, Zemlicka J.
J Med Chem (2006) 49 : 6120 -6128
PubMed 17004726 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.60 5.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL384629 1 5.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL384629 EC50 = 2500.0 nM 5.60