Assay Detail
Binding
CHEMBL854182
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to EP2 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Prostaglandin E2 receptor EP2 subtype (CHEMBL1881) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification of an indole series of prostaglandin D2 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.53 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL383484 | — | — | 1 | 6.64 |
| CHEMBL207203 | — | — | 1 | 6.41 |
| CHEMBL208260 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL383484 | — | Ki | = | 230.0 | nM | 6.64 |
| CHEMBL207203 | — | Ki | = | 390.0 | nM | 6.41 |
| CHEMBL208260 | — | Ki | > | 4600.0 | nM | - |