Assay Detail
Binding
CHEMBL854246
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CA2 by 4-nitrophenyl acetate hydrolysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.20 | 5.76 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL168778 | — | — | 1 | 5.76 |
| CHEMBL168514 | PHENYLSULFAMIDE | — | 1 | 5.10 |
| CHEMBL165878 | — | — | 1 | 4.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL168778 | — | Ki | = | 1740.0 | nM | 5.76 |
| CHEMBL168514 | PHENYLSULFAMIDE | Ki | = | 8020.0 | nM | 5.10 |
| CHEMBL165878 | — | Ki | = | 18800.0 | nM | 4.73 |