Assay Detail
Binding
CHEMBL854247
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Binding affinity to human CA2 in presence of sodium sulfate and ANS at pH 7.5 by ThermoFluor assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 5.76 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL168778 | — | — | 1 | 6.00 |
| CHEMBL168514 | PHENYLSULFAMIDE | — | 1 | 5.70 |
| CHEMBL165878 | — | — | 1 | 5.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL168778 | — | Kd | = | 1000.0 | nM | 6.00 |
| CHEMBL168514 | PHENYLSULFAMIDE | Kd | = | 2000.0 | nM | 5.70 |
| CHEMBL165878 | — | Kd | = | 2650.0 | nM | 5.58 |