Assay Detail
Functional
CHEMBL855161
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at bradykinin B1 receptor assessed as prevention of Lys-desArg9-Bk-induced contraction in human umbilical vein
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Umbilical vein |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Identification of a nonpeptidic and conformationally restricted bradykinin B1 receptor antagonist with anti-inflammatory activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 7.40 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL415848 | — | — | 1 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL415848 | — | Kd | = | 39.81 | nM | 7.40 |