Assay Detail
Functional
CHEMBL855630
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Cytotoxicity against Vero cells by MTT assay after 3 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chlorocebus sabaeus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and preliminary evaluation of doxazolidine carbamates as prodrugs activated by carboxylesterases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.53 | 8.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL217089 | DOXAZOLIDINE | — | 1 | 8.20 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.00 |
| CHEMBL384221 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL217089 | DOXAZOLIDINE | IC50 | = | 6.31 | nM | 8.20 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL384221 | — | IC50 | = | 3981.07 | nM | 5.40 |