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Assay Detail

CHEMBL855674

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of mushroom tyrosinase at 18.4 uM
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Agaricus bisporus
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Tyrosinase (CHEMBL3318)
Type SINGLE PROTEIN
Organism Agaricus bisporus

Publication

Chemical transformations of oxyresveratrol (trans-2,4,3',5'-tetrahydroxystilbene) into a potent tyrosinase inhibitor and a strong cytotoxic agent.
Likhitwitayawuid K, Sornsute A, Sritularak B, Ploypradith P.
Bioorg Med Chem Lett (2006) 16 : 5650 -5653
PubMed 16919455 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.55 4.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL43065 OXYRESVERATROL 1 4.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL43065 OXYRESVERATROL Ki = 28000.0 nM 4.55