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Assay Detail

CHEMBL856034

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Binding
Dissociation constant against dihydroorotate dehydrogenase 1A (1A DHOD) from Lactococcus lactis at 25 degrees C pH 8.0
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Lactococcus lactis
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Specific inhibition of a family 1A dihydroorotate dehydrogenase by benzoate pyrimidine analogues.
Palfey BA, Björnberg O, Jensen KF.
J Med Chem (2001) 44 : 2861 -2864
PubMed 11520193 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 4.74 4.74

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL95308 3,5-DIHYDROXYBENZOIC ACID 1 4.74

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL95308 3,5-DIHYDROXYBENZOIC ACID Kd = 18400.0 nM 4.74