Assay Detail

CHEMBL856219

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Functional

Inhibitory concentration against A549 human lung carcinoma cell line; Range is 2-5 nM

ChEMBL ↗

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Target

A549 (CHEMBL392) ↗

Open DB target context

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Primary target A549

CHEMBL392

Anchored from Assay target.

Protein identity A549

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	A549
Confidence	1 — Organism
Curated By	Intermediate

Target

A549 (CHEMBL392) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Joys of molecules. 2. Endeavors in chemical biology and medicinal chemistry.

Nicolaou KC.
J Med Chem (2005) 48 : 5613 -5638
PubMed 16134928 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	8.30	8.30

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL403166	DIAZONAMIDE A	—	2	8.30

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL403166	DIAZONAMIDE A	IC50	=	5.0	nM	8.30
CHEMBL403166	DIAZONAMIDE A	IC50	=	5.0	nM	8.30