Assay Detail
Binding
CHEMBL856321
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]NDP-MSH from human MC1R stably expressed in HEK293 cells
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Melanocyte-stimulating hormone receptor (CHEMBL3795) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Propionylpiperazines as human melanocortin-4 receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 1 | - | - |
| Ki | 1 | 5.51 | 5.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL213122 | — | — | 1 | 5.51 |
| CHEMBL377231 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL213122 | — | Ki | = | 3100.0 | nM | 5.51 |
| CHEMBL377231 | — | Activity | = | 23.0 | % | - |