Assay Detail
Binding
CHEMBL856323
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]NDP-MSH from human MC5R stably expressed in HEK293 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Propionylpiperazines as human melanocortin-4 receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.54 | 7.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL377231 | — | — | 1 | 7.07 |
| CHEMBL213122 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL377231 | — | Ki | = | 86.0 | nM | 7.07 |
| CHEMBL213122 | — | Ki | = | 1000.0 | nM | 6.00 |