Assay Detail
Binding
CHEMBL856332
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Inhibition of DPP4
9
Total Activities
8
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and dipeptidyl peptidase inhibition of N-(4-substituted-2,4-diaminobutanoyl)piperidines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | - | - |
| Ki | 1 | 10.09 | 10.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL98869 | — | — | 2 | 10.09 |
| CHEMBL215299 | — | — | 1 | - |
| CHEMBL213514 | — | — | 1 | - |
| CHEMBL214630 | — | — | 1 | - |
| CHEMBL214580 | — | — | 1 | - |
| CHEMBL373665 | — | — | 1 | - |
| CHEMBL215244 | — | — | 1 | - |
| CHEMBL215824 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL98869 | — | Ki | = | 0.082 | nM | 10.09 |
| CHEMBL215299 | — | IC50 | = | 325000.0 | nM | - |
| CHEMBL213514 | — | IC50 | > | 125000.0 | nM | - |
| CHEMBL214630 | — | IC50 | > | 125000.0 | nM | - |
| CHEMBL214580 | — | IC50 | = | 234000.0 | nM | - |
| CHEMBL373665 | — | IC50 | > | 125000.0 | nM | - |
| CHEMBL215244 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL215824 | — | IC50 | > | 250000.0 | nM | - |
| CHEMBL98869 | — | IC50 | = | 196000.0 | nM | - |