Assay Detail
Functional
CHEMBL856344
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Cytotoxicity against human bone marrow cells assessed as inhibition of colony forming unit of granulocyte/macrophage
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Osteoclast-like |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Discovery of a novel series of inhibitors of human cytomegalovirus primase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.59 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5314375 | CIDOFOVIR | 4.0 | 1 | 5.00 |
| CHEMBL385412 | — | — | 1 | 4.52 |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | 4.52 |
| CHEMBL385536 | — | — | 1 | 4.52 |
| CHEMBL215727 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5314375 | CIDOFOVIR | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL385412 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL182 | GANCICLOVIR | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL385536 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL215727 | — | IC50 | = | 40000.0 | nM | 4.40 |