Assay Detail
Binding
CHEMBL856507
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of c-RAF
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
RAF proto-oncogene serine/threonine-protein kinase (CHEMBL1906) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Aza-stilbenes as potent and selective c-RAF inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.40 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL218791 | — | — | 1 | 8.40 |
| CHEMBL216668 | — | — | 1 | 6.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL218791 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL216668 | — | IC50 | = | 400.0 | nM | 6.40 |