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Assay Detail

CHEMBL856953

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity towards Bradykinin receptor B2 in human S34 clone cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type S34
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

B2 bradykinin receptor (CHEMBL3157)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Bradykinin receptor antagonists containing N-substituted amino acids: in vitro and in vivo B(2) and B(1) receptor antagonist activity.
Goodfellow VS, Marathe MV, Kuhlman KG, Fitzpatrick TD, Cuadrado D, Hanson W, Zuzack JS, Ross SE, Wieczorek M, Burkard M, Whalley ET.
J Med Chem (1996) 39 : 1472 -1484
PubMed 8691478 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.62 9.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3038099 1 9.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3038099 Ki = 0.2399 nM 9.62