Assay Detail
Functional
CHEMBL857134
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Effective concentration against mouse Melanocortin 3 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.56 | 8.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL266288 | — | — | 1 | 8.90 |
| CHEMBL428134 | — | — | 1 | 8.08 |
| CHEMBL2370695 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL266288 | — | Kd | = | 1.259 | nM | 8.90 |
| CHEMBL428134 | — | Kd | = | 8.318 | nM | 8.08 |
| CHEMBL2370695 | — | Kd | = | 1995.26 | nM | 5.70 |