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Assay Detail

CHEMBL857516

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The apparent Ki value against NS3-4Apep protease
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Hepacivirus hominis
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

Hepatitis C virus serine protease, NS3/NS4A (CHEMBL2095231)
Type PROTEIN COMPLEX
Organism Hepatitis C virus

Publication

Peptide-based inhibitors of the hepatitis C virus serine protease.
Llinàs-Brunet M, Bailey M, Fazal G, Goulet S, Halmos T, Laplante S, Maurice R, Poirier M, Poupart MA, Thibeault D, Wernic D, Lamarre D.
Bioorg Med Chem Lett (1998) 8 : 1713 -1718
PubMed 9873421 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.22 6.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2370476 1 6.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2370476 Ki = 600.0 nM 6.22