Assay Detail
Functional
CHEMBL857560
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In vivo antimalarial activity against Plasmodium falciparum D6
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Dispiro-1,2,4,5-tetraoxanes: a new class of antimalarial peroxides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.85 | 8.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL278291 | WR-148999 | — | 1 | 8.16 |
| CHEMBL93291 | — | — | 1 | 8.09 |
| CHEMBL96830 | — | — | 1 | 7.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL278291 | WR-148999 | IC50 | = | 6.9 | nM | 8.16 |
| CHEMBL93291 | — | IC50 | = | 8.2 | nM | 8.09 |
| CHEMBL96830 | — | IC50 | = | 50.0 | nM | 7.30 |