Assay Detail
Binding
CHEMBL857667
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against platelet-derived growth factor receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
Platelet-derived growth factor receptor (CHEMBL2095189) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
Designed multiple ligands. An emerging drug discovery paradigm.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.87 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL20867 | — | — | 1 | 8.00 |
| CHEMBL941 | IMATINIB | 4.0 | 1 | 7.30 |
| CHEMBL277931 | — | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL20867 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL941 | IMATINIB | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL277931 | — | IC50 | = | 5000.0 | nM | 5.30 |