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Assay Detail

CHEMBL857974

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against human 5-hydroxytryptamine 1B receptor cloned receptors in CHO cells using [3H]5-CT as radioligand
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type CHO
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 1B (CHEMBL1898)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A novel ergot alkaloid as a 5-HT(1A) inhibitor produced by Dicyma sp.
Vázquez MJ, Roa AM, Reyes F, Vega A, Rivera-Sagredo A, Thomas DR, Díez E, Hueso-Rodríguez JA.
J Med Chem (2003) 46 : 5117 -5120
PubMed 14613313 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.50 6.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL146942 1 6.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL146942 Ki = 316.23 nM 6.50