Assay Detail
Binding
CHEMBL858909
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Binding affinity to human BK1 receptor D291 mutant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
5-Piperazinyl pyridine carboxamide bradykinin B1 antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.16 | 10.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL189123 | — | — | 1 | 10.31 |
| CHEMBL425588 | — | — | 1 | 10.10 |
| CHEMBL207011 | — | — | 1 | 7.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL189123 | — | Ki | = | 0.049 | nM | 10.31 |
| CHEMBL425588 | — | Ki | = | 0.08 | nM | 10.10 |
| CHEMBL207011 | — | Ki | = | 85.0 | nM | 7.07 |