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Assay Detail

CHEMBL859007

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antibacterial activity against Clavibacter michiganensis
8
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Clavibacter michiganensis
Confidence 1 — Organism
Curated By Intermediate

Target

Clavibacter michiganensis (CHEMBL613849)
Type ORGANISM
Organism Clavibacter michiganensis

Publication

A minimalist design approach to antimicrobial agents based on a thionin template.
Vila-Perelló M, Tognon S, Sánchez-Vallet A, García-Olmedo F, Molina A, Andreu D.
J Med Chem (2006) 49 : 448 -451
PubMed 16420028 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 8 6.29 7.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4299737 2 7.52
CHEMBL269753 1 6.29
CHEMBL412491 1 6.13
CHEMBL372354 1 6.05
CHEMBL219285 1 6.05
CHEMBL373375 1 5.49
CHEMBL219374 1 5.29

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4299737 EC50 = 30.0 nM 7.52
CHEMBL4299737 EC50 = 30.0 nM 7.52
CHEMBL269753 EC50 = 510.0 nM 6.29
CHEMBL412491 EC50 = 740.0 nM 6.13
CHEMBL372354 EC50 = 900.0 nM 6.05
CHEMBL219285 EC50 = 900.0 nM 6.05
CHEMBL373375 EC50 = 3270.0 nM 5.49
CHEMBL219374 EC50 = 5130.0 nM 5.29