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Assay Detail

CHEMBL859012

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antifungal activity against Botrytis cinerea
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Botrytis cinerea
Confidence 1 — Organism
Curated By Intermediate

Target

Botrytis cinerea (CHEMBL612399)
Type ORGANISM
Organism Botrytis cinerea

Publication

A minimalist design approach to antimicrobial agents based on a thionin template.
Vila-Perelló M, Tognon S, Sánchez-Vallet A, García-Olmedo F, Molina A, Andreu D.
J Med Chem (2006) 49 : 448 -451
PubMed 16420028 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 7 6.34 7.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4299737 1 7.10
CHEMBL412491 1 6.72
CHEMBL269753 1 6.70
CHEMBL219285 1 6.40
CHEMBL372354 1 6.26
CHEMBL373375 1 5.80
CHEMBL219374 1 5.39

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4299737 EC50 = 80.0 nM 7.10
CHEMBL412491 EC50 = 190.0 nM 6.72
CHEMBL269753 EC50 = 200.0 nM 6.70
CHEMBL219285 EC50 = 400.0 nM 6.40
CHEMBL372354 EC50 = 550.0 nM 6.26
CHEMBL373375 EC50 = 1600.0 nM 5.80
CHEMBL219374 EC50 = 4100.0 nM 5.39