Assay Detail
Functional
CHEMBL859117
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against HUVEC cell line
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HUVEC |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Miliusanes, a class of cytotoxic agents from Miliusa sinensis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.59 | 5.88 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL382849 | — | — | 1 | 5.88 |
| CHEMBL381302 | — | — | 1 | 5.75 |
| CHEMBL440759 | — | — | 1 | 5.54 |
| CHEMBL425038 | — | — | 1 | 5.18 |
| CHEMBL201579 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL382849 | — | IC50 | = | 1320.0 | nM | 5.88 |
| CHEMBL381302 | — | IC50 | = | 1790.0 | nM | 5.75 |
| CHEMBL440759 | — | IC50 | = | 2890.0 | nM | 5.54 |
| CHEMBL425038 | — | IC50 | = | 6550.0 | nM | 5.18 |
| CHEMBL201579 | — | IC50 | > | 10900.0 | nM | - |