Assay Detail
Functional
CHEMBL859990
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Intrinsic activity against dopamine D2(short) receptor expressed in CHO cells by GTPgammaS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and biological investigations of dopaminergic partial agonists preferentially recognizing the D4 receptor subtype.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.07 | 7.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL378455 | — | — | 1 | 7.50 |
| CHEMBL240773 | QUINPIROLE | 2.0 | 1 | 6.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL378455 | — | EC50 | = | 32.0 | nM | 7.50 |
| CHEMBL240773 | QUINPIROLE | EC50 | = | 230.0 | nM | 6.64 |