Assay Detail
Binding
CHEMBL860741
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]L-364718 from human recombinant CCK1 receptor expressed in CHO cell line
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Novel, achiral 1,3,4-benzotriazepine analogues of 1,4-benzodiazepine-based CCK(2) antagonists that display high selectivity over CCK(1) receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.44 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL378388 | — | — | 1 | 5.82 |
| CHEMBL381805 | — | — | 1 | 5.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL378388 | — | Ki | = | 1513.56 | nM | 5.82 |
| CHEMBL381805 | — | Ki | = | 8709.64 | nM | 5.06 |