Assay Detail
Functional
CHEMBL861247
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Efficacy against human recombinant 5HT2C receptor induced intracellular calcium mobilization in CHO cells by FLIPR
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and biological evaluation of novel hexahydro-pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazines as potent and selective 5-HT(2C) receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.82 | 7.82 |
| Emax | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL203013 | — | — | 2 | 7.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL203013 | — | EC50 | = | 15.0 | nM | 7.82 |
| CHEMBL203013 | — | Emax | = | 90.0 | % | - |