Assay Detail
Functional
CHEMBL861452
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cell to cell spread of HSV1
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human herpesvirus 1 strain KOS |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, biological activity, and preliminary pharmacokinetic evaluation of analogues of a phosphosulfomannan angiogenesis inhibitor (PI-88).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 5.81 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL198643 | — | — | 1 | 6.40 |
| CHEMBL382044 | — | — | 1 | 6.00 |
| CHEMBL262707 | — | — | 1 | 5.52 |
| CHEMBL265885 | — | — | 1 | 5.30 |
| CHEMBL373279 | — | — | 1 | - |
| CHEMBL264593 | — | — | 1 | - |
| CHEMBL438743 | — | — | 1 | - |
| CHEMBL412087 | — | — | 1 | - |
| CHEMBL405383 | — | — | 1 | - |
| CHEMBL264125 | — | — | 1 | - |
| CHEMBL413401 | — | — | 1 | - |
| CHEMBL425275 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL198643 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL382044 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL262707 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL265885 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL373279 | — | IC50 | - | — | - | |
| CHEMBL264593 | — | IC50 | - | — | - | |
| CHEMBL438743 | — | IC50 | - | — | - | |
| CHEMBL412087 | — | IC50 | - | — | - | |
| CHEMBL405383 | — | IC50 | - | — | - | |
| CHEMBL264125 | — | IC50 | - | — | - | |
| CHEMBL413401 | — | IC50 | - | — | - | |
| CHEMBL425275 | — | IC50 | - | — | - |