Assay Detail
Functional
CHEMBL861682
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of anti-CD3 antibody-induced IL2 production in mouse EL4 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | EL4 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.60 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL382362 | — | — | 1 | 6.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL382362 | — | IC50 | = | 250.0 | nM | 6.60 |