Assay Detail
Functional
CHEMBL861902
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Protein binding in Huh7 cells using HCV 1b replicon by a replicon cell assay in presence of HSA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Cell Type | Huh-7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
3-(1,1-dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.89 | 4.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL372357 | — | — | 1 | 4.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL372357 | — | EC50 | = | 13000.0 | nM | 4.89 |