Assay Detail
Functional
CHEMBL862228
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Reduction in the phospho-histone H3 positive cells in mice bearing human colorectal carcinoma SW620 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SW-620 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Discovery of novel and potent thiazoloquinazolines as selective Aurora A and B kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.70 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL201307 | — | — | 1 | 8.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL201307 | — | IC50 | = | 2.0 | nM | 8.70 |