Assay Detail
Functional
CHEMBL862397
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding to human V2 receptor expressed in LV2 cells by cAMP production
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LV2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Pyridobenzodiazepines: a novel class of orally active, vasopressin V2 receptor selective agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 9.40 | 10.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL373742 | VASOPRESSIN | 4.0 | 1 | 10.28 |
| CHEMBL363910 | — | — | 1 | 9.13 |
| CHEMBL201889 | — | — | 1 | 8.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL373742 | VASOPRESSIN | EC50 | = | 0.052 | nM | 10.28 |
| CHEMBL363910 | — | EC50 | = | 0.74 | nM | 9.13 |
| CHEMBL201889 | — | EC50 | = | 1.67 | nM | 8.78 |