Assay Detail
Binding
CHEMBL862398
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]AVP from human V1a receptor expressed in CHO cells
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Pyridobenzodiazepines: a novel class of orally active, vasopressin V2 receptor selective agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.69 | 6.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL363910 | — | — | 1 | 6.11 |
| CHEMBL203513 | — | — | 1 | 5.75 |
| CHEMBL201889 | — | — | 1 | 5.22 |
| CHEMBL373199 | — | — | 1 | - |
| CHEMBL381458 | — | — | 1 | - |
| CHEMBL381763 | — | — | 1 | - |
| CHEMBL378143 | — | — | 1 | - |
| CHEMBL202106 | — | — | 1 | - |
| CHEMBL202105 | — | — | 1 | - |
| CHEMBL201890 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL363910 | — | IC50 | = | 778.0 | nM | 6.11 |
| CHEMBL203513 | — | IC50 | = | 1783.0 | nM | 5.75 |
| CHEMBL201889 | — | IC50 | = | 5954.0 | nM | 5.22 |
| CHEMBL373199 | — | IC50 | - | — | - | |
| CHEMBL381458 | — | IC50 | - | — | - | |
| CHEMBL381763 | — | IC50 | - | — | - | |
| CHEMBL378143 | — | IC50 | - | — | - | |
| CHEMBL202106 | — | IC50 | - | — | - | |
| CHEMBL202105 | — | IC50 | - | — | - | |
| CHEMBL201890 | — | IC50 | - | — | - |