Assay Detail
Binding
CHEMBL862620
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human cloned adrenergic alpha-1A receptor by radioligand binding assay
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Evaluation of the eutomer of 4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one, {(+)-SYA 09}, a pyrrolidine analog of haloperidol.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.27 | 7.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL150161 | — | — | 2 | 7.47 |
| CHEMBL210578 | — | — | 1 | 7.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL150161 | — | Ki | = | 34.0 | nM | 7.47 |
| CHEMBL210578 | — | Ki | = | 39.3 | nM | 7.41 |
| CHEMBL150161 | — | Ki | = | 114.8 | nM | 6.94 |