Assay Detail
Functional
CHEMBL862763
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of IFN-gamma-stimulated expression of beta-2 microglobulin
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design and preparation of 2-benzamido-pyrimidines as inhibitors of IKK.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.25 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200027 | — | — | 1 | 5.70 |
| CHEMBL200229 | — | — | 1 | 5.70 |
| CHEMBL200832 | — | — | 1 | 5.70 |
| CHEMBL371543 | — | — | 1 | 5.30 |
| CHEMBL200462 | — | — | 1 | 5.30 |
| CHEMBL200106 | — | — | 1 | 5.30 |
| CHEMBL382752 | — | — | 1 | 5.00 |
| CHEMBL200946 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200027 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL200229 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL200832 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL371543 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL200462 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL200106 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL382752 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL200946 | — | IC50 | = | 100000.0 | nM | 4.00 |