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Assay Detail

CHEMBL862858

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of MCP1-induced chemotaxis of mouse primary monocytes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type Monocyte
Confidence 1 — Organism
Curated By Expert

Target

Monocyte (CHEMBL5314323)
Type CELL-LINE
Organism Mus musculus

Publication

Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma.
Pomel V, Klicic J, Covini D, Church DD, Shaw JP, Roulin K, Burgat-Charvillon F, Valognes D, Camps M, Chabert C, Gillieron C, Françon B, Perrin D, Leroy D, Gretener D, Nichols A, Vitte PA, Carboni S, Rommel C, Schwarz MK, Rückle T.
J Med Chem (2006) 49 : 3857 -3871
PubMed 16789742 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.28 4.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL379156 1 4.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL379156 IC50 = 53000.0 nM 4.28